BDBM608356 (Z)-15-chloro-96-fluoro-13,21,25,61- tetramethyl-11H,21H,61H-10-oxa-4,8-dithia- 1(4,1)-indola-2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 14::US11691989, Compound 15::US11691989, Compound 16
SMILES Cc1c-2c(CSCc3cc(CSc4cc(OCCCn5c(C(O)=O)c(C)c6c-2c(Cl)ccc56)c2ccc(F)cc2c4)n(C)n3)nn1C
InChI Key InChIKey=ISYYATNNMXPQEK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 608356
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 19nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 2nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 3.20E+3nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair