BDBM608337 US11691981, Compound 74

SMILES C[C@H]1CC(C[C@@H](C)O1)c1nn(cc1Oc1ccnc(Nc2ccnc(c2)C(C)(C)O)c1)C1CC1

InChI Key InChIKey=HZEIXMYDPZYRLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608337   

TargetTGF-beta receptor type-1(Human)
Inventisbio

US Patent
LigandPNGBDBM608337(US11691981, Compound 74)
Affinity DataIC50: 17nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent