BDBM608308 US11691981, Compound 65

SMILES Cc1nc(ccc1Oc1ccnc(Nc2ccnc(c2)C(C)(C)O)c1)C(F)(F)F

InChI Key InChIKey=YNIRZYJUQMHOIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608308   

TargetTGF-beta receptor type-1(Human)
Inventisbio

US Patent
LigandPNGBDBM608308(US11691981, Compound 65)
Affinity DataIC50: 14nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent