BDBM605189 (3S,6S)-3-{(2S,3S)-2-[2-(2-Fluoro- ethoxy)-acetylamino]-3-methyl- pentanoylamino}-4-oxo-1,2,3,4,6,7- hexahydro-[1,4]diazepino[3,2,1- hi]indole-6-carboxylic acid (1H- [1,2,3]triazol-4-ylmethyl)-amide::US11667645, Compound C143

SMILES CC[C@H](C)[C@H](NC(=O)COCCF)C(=O)N[C@H]1CNc2cccc3C[C@H](N(c23)C1=O)C(=O)NCc1c[nH]nn1

InChI Key InChIKey=GXKIQCNQYVLLPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605189   

TargetGranzyme B(Human)
Cytosite Biopharma

US Patent
LigandPNGBDBM605189((3S,6S)-3-{(2S,3S)-2-[2-(2-Fluoro- ethoxy)-acetyla...)
Affinity DataIC50: 150nMAssay Description:Buffer pH7.4: Prepare 1 (M) KH2PO4 and 1 (M) K2HPO4. Titrate 1(M) K2HPO4 with 1 (M) KH2PO4 to obtain pH 7.40. Dilute this buffer 10 fold in Water (30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
Go to US Patent