BDBM605112 (2S,5S)-5-((S)-2-Benzoylamino-4,4,4- trifluoro-3-methyl-butyrylamino)-4- oxo-1,2,4,5,6,7-hexahydro- azepino[3,2,1-hi]indole-2-carboxylic acid (1H-[1,2,3]triazol-4-ylmethyl)- amide::US11667645, Compound C055

SMILES CC([C@H](NC(=O)c1ccccc1)C(=O)N[C@H]1CCc2cccc3C[C@H](N(c23)C1=O)C(=O)NCc1c[nH]nn1)C(F)(F)F

InChI Key InChIKey=DGAWOIWSMNVKLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 605112   

TargetGranzyme B(Human)
Cytosite Biopharma

US Patent
LigandPNGBDBM605112((2S,5S)-5-((S)-2-Benzoylamino-4,4,4- trifluoro-3-m...)
Affinity DataIC50: 150nMAssay Description:Buffer pH7.4: Prepare 1 (M) KH2PO4 and 1 (M) K2HPO4. Titrate 1(M) K2HPO4 with 1 (M) KH2PO4 to obtain pH 7.40. Dilute this buffer 10 fold in Water (30...More data for this Ligand-Target Pair
In DepthDetails
US Patent