BDBM605055 US11667643, Compound I-90::US11667643, Compound I-92

SMILES CC(C)(O)C#Cc1ccc2OCC(NC(=O)c3n[nH]c(Cc4ccccc4)n3)c3nccn3-c2c1

InChI Key InChIKey=KETVFYKDZUHJOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605055   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM605055(US11667643, Compound I-90 | US11667643, Compound I...)
Affinity DataIC50: 53.1nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM605055(US11667643, Compound I-90 | US11667643, Compound I...)
Affinity DataIC50: 28.2nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
Go to US Patent