BDBM603961 US11655252, Compound ID

SMILES OCCCn1cc(Nc2nccc(n2)N2CC3CCC(C2)N3C(=O)[C@@H]2CC2(F)F)cn1

InChI Key InChIKey=WZWCBXAGYDGWST-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 603961   

TargetTyrosine-protein kinase JAK1(Human)
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50: 47nMAssay Description:Compounds of the invention were evaluated by in vitro methods to determine their respective ability to inhibit the JAK kinases (TYK2, JAK1, JAK2, JAK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50: 81nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50: 9.29E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Pfizer

US Patent
LigandPNGBDBM603961(US11655252, Compound ID)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
Go to US Patent