BDBM602750 Synthesis of (E)-6-((2-(aminomethyl)-3-fluoroallyl)oxy)-2-cyclopropyl-3,4-dihydroisoquinolin-1(2H)-one ::US11649233, Compound 5

SMILES NC\C(COc1ccc2C(=O)N(CCc2c1)C1CC1)=C/F

InChI Key InChIKey=LLKHNXOEBPVMPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 602750   

TargetAmine oxidase [copper-containing] 3(Human)
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM602750(US11649233, Compound 5 | Synthesis of (E)-6-((2-(a...)
Affinity DataIC50: 18nMAssay Description:Test substances: the compounds of the present invention shown in Table 1 and prepared according to the methods of the examples 1. Inhibition Activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM602750(US11649233, Compound 5 | Synthesis of (E)-6-((2-(a...)
Affinity DataIC50: 6.30E+3nMAssay Description:Test substances: the compounds of the present invention shown in Table 1 and prepared according to the methods of the examples 1. Inhibition Activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM602750(US11649233, Compound 5 | Synthesis of (E)-6-((2-(a...)
Affinity DataIC50: 1.30E+3nMAssay Description:Test substances: the compounds of the present invention shown in Table 1 and prepared according to the methods of the examples 1. Inhibition Activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent