BDBM6009 3-Ethyl-6-(pyrid-3-ylmethyl)-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one::3-ethyl-6-(pyridin-3-ylmethyl)-1-(2,4,6-trichlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one::pyrazolo[3,4-d]pyrimidin-4-one deriv. 19i

SMILES CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3cccnc3)[nH]c(=O)c12

InChI Key InChIKey=RVQZIDJAMAEGLG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6009   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM6009(3-ethyl-6-(pyridin-3-ylmethyl)-1-(2,4,6-trichlorop...)
Affinity DataIC50: 1.30E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM6009(3-ethyl-6-(pyridin-3-ylmethyl)-1-(2,4,6-trichlorop...)
Affinity DataIC50: 17nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM6009(3-ethyl-6-(pyridin-3-ylmethyl)-1-(2,4,6-trichlorop...)
Affinity DataIC50: 220nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed