BDBM600758 US11633395, Example 2

SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1cn2ccnc2cn1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=FWAZIKLKGRZMDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600758   

TargetMetabotropic glutamate receptor 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM600758(US11633395, Example 2)
Affinity DataIC50: 11nMAssay Description:Human mGlu2 receptor stable expressing cells were prepared and incubated. Luminescence signals by mGlu2 receptor stimulation were detected with FDSS7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent