BDBM6006 6-(3-(Ethoxycarbonylmethyl)benzyl)-3-ethyl-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one::ethyl 2-(3-{[3-ethyl-4-oxo-1-(2,4,6-trichlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-6-yl]methyl}phenyl)acetate::pyrazolo[3,4-d]pyrimidin-4-one deriv. 19f

SMILES CCOC(=O)Cc1cccc(Cc2nc3n(nc(CC)c3c(=O)[nH]2)-c2c(Cl)cc(Cl)cc2Cl)c1

InChI Key InChIKey=GZHDLDXIEMGQNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6006   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM6006(6-(3-(Ethoxycarbonylmethyl)benzyl)-3-ethyl-1-(2,4,...)
Affinity DataIC50: 1.90E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM6006(6-(3-(Ethoxycarbonylmethyl)benzyl)-3-ethyl-1-(2,4,...)
Affinity DataIC50: 150nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2005
Entry Details Article
PubMed