BDBM598027 Tetrahydro-2H-pyran-4-yl(8-amino-7- fluoro-6-(8-methyl-2,3-dihydro-1H- pyrido[2,3-b][1,4]oxazin-7- yl)isoquinolin-3-yl)carbamate::US11612606, Compound 401

SMILES Cc1c2NCCOc2ncc1-c1cc2cc(NC(=O)OC3CCOCC3)ncc2c(N)c1F

InChI Key InChIKey=MXQDOIPMFYATOE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 598027   

TargetLymphocyte cytosolic protein 2(Human)
Genentech

US Patent
LigandPNGBDBM598027(US11612606, Compound 401 | Tetrahydro-2H-pyran-4-y...)
Affinity DataIC50: 97nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
Go to US Patent

LigandPNGBDBM598027(US11612606, Compound 401 | Tetrahydro-2H-pyran-4-y...)
Affinity DataKi:  0.0190nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
Go to US Patent