BDBM597754 US11608309, Compound 4
SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)N(C)C)ccc1O
InChI Key InChIKey=LWVNHDCBDHNESR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 597754
TargetMatrix metalloproteinase-9(Human)
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: 1.70E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase (MMP2)(Human)
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
TargetCollagenase 3 (MMP13)(Human)
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair