BDBM597671 5-(5-cyclopropylisoxazol-3- yl)-7-(oxetan-3-yl)-7H- pyrrolo[2,3-d]pyrimidin-4- amine::US11603374, Example 26
SMILES Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)C1COC1
InChI Key InChIKey=TXBBYTSVSXMIOO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 597671
Affinity DataIC50: 2.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Affinity DataIC50: 12.9nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Affinity DataIC50: 27.7nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair