BDBM597564 US11597733, Example 30-19

SMILES COc1nc(ccc1-c1cnc2sc(nn12)N1C[C@H]2OCC[C@H](N)[C@H]2C1)C(C)C

InChI Key InChIKey=NRAZFBZLVJVBEY-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 597564   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Novartis

US Patent
LigandPNGBDBM597564(US11597733, Example 30-19)
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM597564(US11597733, Example 30-19)
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Novartis

US Patent
LigandPNGBDBM597564(US11597733, Example 30-19)
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
Go to US Patent