BDBM595832 US11591336, Compound 13::US11629145, Compound 11

SMILES CC1(N)CCN(CC1)c1cnc2c(Sc3cccc(Cl)c3Cl)n[nH]c2n1

InChI Key InChIKey=JTHMZNHORYALTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595832   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
D. E. Shaw Research

US Patent
LigandPNGBDBM595832(US11629145, Compound 11 | US11591336, Compound 13)
Affinity DataIC50: 1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
D. E. Shaw Research

US Patent
LigandPNGBDBM595832(US11629145, Compound 11 | US11591336, Compound 13)
Affinity DataIC50: 1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent