BDBM595550 US11591319, ID lqr-9-161

SMILES Brc1ccc(cc1)C(=O)N1N=C(CC1c1ccccc1)c1ccc(NC(=O)OC2CC2)cc1

InChI Key InChIKey=WNBYRVPKAWRQRZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 595550   

TargetBeclin 1/Bcl-2(Human)
University Of Texas

US Patent
LigandPNGBDBM595550(US11591319, ID lqr-9-161)
Affinity DataIC50: 156nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM595550(US11591319, ID lqr-9-161)
Affinity DataIC50: 44nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM595550(US11591319, ID lqr-9-161)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of biotin-linker-Bax BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21 Star...More data for this Ligand-Target Pair
In DepthDetails
PubMed