BDBM595539 US11591319, ID lqr-9-076::US11591319, ID lqr-9-085
SMILES CC(C)NC(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccccc1)C(=O)c1ccc(Br)cc1
InChI Key InChIKey=SUEZXPXGAIMTGO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 595539
Affinity DataIC50: 349nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Human)
University of Texas Southwestern Medical Center
Curated by ChEMBL
University of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair