BDBM595513 US11591319, ID lqr-8-231

SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccco1)C(=O)c1ccc(Br)cc1

InChI Key InChIKey=SHUCWWLORPYDRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595513   

TargetBeclin 1/Bcl-2(Human)
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM595513(US11591319, ID lqr-8-231)
Affinity DataIC50: 982nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM595513(US11591319, ID lqr-8-231)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
In DepthDetails
PubMed