BDBM595007 US11584714, Compound 1034

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCN2C(=O)[C@H]2Cc3ccccc3CN2)cc1

InChI Key InChIKey=XIGSMDSKPRCHIQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 595007   

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595007(US11584714, Compound 1034)
Affinity DataKi: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595007(US11584714, Compound 1034)
Affinity DataKi: <500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

Targetthrombin(Human)
Omeros

US Patent
LigandPNGBDBM595007(US11584714, Compound 1034)
Affinity DataKi:  1.50E+3nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

Targetthrombin(Human)
Omeros

US Patent
LigandPNGBDBM595007(US11584714, Compound 1034)
Affinity DataKi: <2.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent