BDBM594976 US11584714, Compound 1003

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCN2C(=O)C2CCCN2)cc1

InChI Key InChIKey=OZNFKJCRCCRVFH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594976   

Targetthrombin(Human)
Omeros

US Patent
LigandPNGBDBM594976(US11584714, Compound 1003)
Affinity DataKi: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM594976(US11584714, Compound 1003)
Affinity DataKi:  1.50E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent