BDBM594872 US11584755, Example 161

SMILES COc1ccc(cc1)-n1cc(Cn2c3ccsc3c(C(O)=O)c(O)c2=O)c(Br)n1

InChI Key InChIKey=UPPOFHSBRKPFSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594872   

TargetFlap endonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594872(US11584755, Example 161)
Affinity DataIC50: 500nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetExonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594872(US11584755, Example 161)
Affinity DataIC50: 1.50E+3nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent