BDBM594083 (2R)-2-((8R,9aS)-8-amino-1-oxo-5-phenethylhexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl)-N-((5-chloropyridin-2-yl)methyl)-3-cyanopropanamide::US11583538, Example 63

SMILES COC(=O)[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NCCC(=O)CCc1ccccc1

InChI Key InChIKey=QSNZTMLHJFZANZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594083   

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM594083((2R)-2-((8R,9aS)-8-amino-1-oxo-5-phenethylhexahydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM594083((2R)-2-((8R,9aS)-8-amino-1-oxo-5-phenethylhexahydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent