BDBM594066 Synthesis of (R)-2-(3-hydroxy-3-methyl-4-(3-(trimethylsilyl)propoxy)butyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione ::US11584728, Compound M::US12049455, Compound M::US20230303506, Compound M::US20240400529, Compound M

SMILES CC1=C(C)C(=O)C(CC[C@@](C)(O)CCCOCCC[Si](C)(C)C)=C(C)C1=O

InChI Key InChIKey=ZXRAVGDVISDHSB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 594066   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594066(US11584728, Compound M | Synthesis of (R)-2-(3-hyd...)
Affinity DataIC50: 830nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594066(US11584728, Compound M | Synthesis of (R)-2-(3-hyd...)
Affinity DataIC50: 830nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594066(US11584728, Compound M | Synthesis of (R)-2-(3-hyd...)
Affinity DataIC50: 830nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594066(US11584728, Compound M | Synthesis of (R)-2-(3-hyd...)
Affinity DataIC50: 830nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2024
Entry Details
Go to US Patent

TargetLinoleate 9S-lipoxygenase-4(Soybean)
Stealth Biotherapeutics

US Patent
LigandPNGBDBM594066(US11584728, Compound M | Synthesis of (R)-2-(3-hyd...)
Affinity DataIC50: 830nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachidonic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent