BDBM594060 (2R)-2-((8R,9aS)-8-amino-1-oxo-5-phenethylhexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl)-N-(4-chlorobenzyl)-4-methylpentanamide::US11583538, Example 39

SMILES CC(C)C[C@@H](N1CCC(CCc2ccccc2)N2C[C@H](N)C[C@H]2C1=O)C(=O)NCc1ccc(Cl)cc1

InChI Key InChIKey=JVIGRJRYCXXADC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594060   

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM594060((2R)-2-((8R,9aS)-8-amino-1-oxo-5-phenethylhexahydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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