BDBM594043 US11583538, Example 22

SMILES COc1c(CNC(=O)[C@@H](CCC(O)=O)N2CCC(CCc3ccccc3)N3C[C@H](N)C[C@H]3C2=O)ccc(Cl)c1Cl

InChI Key InChIKey=ZURIMLSLQACYGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594043   

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM594043(US11583538, Example 22)
Affinity DataIC50: 1.00E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent