BDBM593701 (S)-4-(4-fluorobenzyl)-N-(5-methyl-7-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-pyrazole-1-carboxamide::US11578078, Compound I-29

SMILES CN1CCC2(CC1)CCN(CC2)c1ccc2OC[C@H](NC(=O)n3cc(Cc4ccc(F)cc4)cn3)C(=O)N(C)c2c1

InChI Key InChIKey=HYMLNHKVNXKAIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593701   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593701((S)-4-(4-fluorobenzyl)-N-(5-methyl-7-(9-methyl-3,9...)
Affinity DataIC50: 48.8nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent