BDBM592694 3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3'-cyclopropyl- 5'-fluoro[biphenyl]-4-carboxamide::US11572374, Example 2-21

SMILES Fc1cc(cc(c1)-c1ccc(C(=O)N[C@@H]2C[C@@H]3CC[C@H]2N3C#N)c(Cl)c1)C1CC1

InChI Key InChIKey=YVAKXAPVTDHHJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592694   

LigandPNGBDBM592694(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50: 62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
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