BDBM592327 2-({[2-(2-methylbiphenyl-3-yl)-6-(2-morpholin-4-ylethoxy)-1,3-benzoxazol-5-yl]methyl}amino)ethanol::US11572366, Example 32

SMILES Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)c(OCCN3CCOCC3)cc2o1

InChI Key InChIKey=VSLGIPZHVMRWRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 592327   

LigandPNGBDBM592327(2-({[2-(2-methylbiphenyl-3-yl)-6-(2-morpholin-4-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM592327(2-({[2-(2-methylbiphenyl-3-yl)-6-(2-morpholin-4-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed