BDBM592178 US11572344, Compound 1.005::US11572344, Example 5

SMILES Fc1cc(I)ccc1Nc1cc(ccc1C(=O)NC1CC1)C#N

InChI Key InChIKey=QLULDHGPNTUUEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592178   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandPNGBDBM592178(US11572344, Example 5 | US11572344, Compound 1.005)
Affinity DataIC50: 1.50E+3nMAssay Description:Reaction buffer: 20mM Hepes (pH 7.5), 10mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02mg/mL BSA, 0.1 mM, Na3VO4, 2mM DTT, 1% DMSO Enzyme: MEK1, Invitrogen c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
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