BDBM590358 5-(4-(9-(2,6-dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)butoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione ::US11560381, Compound D50

SMILES COc1cc(cc(OC)c1CN1CCC2(CC1)CN(CCCCOc1ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c1)CCO2)-c1cn(C)c(=O)c2cnccc12

InChI Key InChIKey=RCEOFBYEJNLUMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590358   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM590358(5-(4-(9-(2,6-dimethoxy-4-(2-methyl-1-oxo-1,2-dihyd...)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent