BDBM590234 US11560385, Compound 10B

SMILES Cc1c(cc(C#CCCC#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2

InChI Key InChIKey=RFQZEKKPJPEAKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590234   

TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590234(US11560385, Compound 10B)
Affinity DataIC50: 50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent