BDBM590213 US11560385, Compound 23A::US11560385, Compound 24A

SMILES Cc1c(C(=O)CN2C3CCC2CC(O)C3)c2ccc(CCS(=O)(=O)C3CC3)cc2n1-c1ccc(Cl)cc1

InChI Key InChIKey=LKPPTJJMUKAJBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 590213   

TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590213(US11560385, Compound 23A | US11560385, Compound 24...)
Affinity DataIC50: 50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590213(US11560385, Compound 23A | US11560385, Compound 24...)
Affinity DataIC50: 75nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
In DepthDetails
US Patent