BDBM589972 US11559538, Example 218::US11559538, Example 219

SMILES CCCOc1cc(cnc1OC)-c1cc(cnc1C)C1COB(O)C1

InChI Key InChIKey=HKWOCFIYTGZBLZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589972   

LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 1.45nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 2.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 3.24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 0.820nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 2.13E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 4.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589972(US11559538, Example 218 | US11559538, Example 219)
Affinity DataIC50: 1.67nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent