BDBM589930 US11559538, Example 178::US11559538, Example 179

SMILES CCCOc1cc(ncc1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=GMDMBHZXTPUZRQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589930   

LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 2.02nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 1.28E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 1.81nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 0.910nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 0.980nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 2.73E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 0.720nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589930(US11559538, Example 178 | US11559538, Example 179)
Affinity DataIC50: 0.740nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent