BDBM589919 US11559538, Example 167::US11559538, Example 168

SMILES CCCOc1c(OC)ccc(-c2cncc(c2)C2COB(O)C2)c1OC

InChI Key InChIKey=MWGMCVGAOBZOPP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589919   

LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 1.98nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 2.79E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 1.37nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 1.13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 0.880nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 1.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 1.17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589919(US11559538, Example 167 | US11559538, Example 168)
Affinity DataIC50: 0.640nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent