BDBM589889 US11559538, Example 141::US11559538, Example 142::US11559538, Example 143

SMILES CCOc1cc(c(F)cc1OC)-c1cncc(C2COB(O)C2)c1C

InChI Key InChIKey=MZGQDWOJCCKITF-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589889   

LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 0.950nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 701nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 3.35nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 2.24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 2.53nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 1.04E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 4.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 2.04nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 2.71nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 1.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 4.11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589889(US11559538, Example 141 | US11559538, Example 143 ...)
Affinity DataIC50: 3.68nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent