BDBM589881 US11559538, Example 133

SMILES CCCOc1cc(ccc1OC)-c1nc(CC(=O)OC)cc(n1)C1COB(O)C1

InChI Key InChIKey=ZLVYXRIKJOCJNF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 589881   

LigandPNGBDBM589881(US11559538, Example 133)
Affinity DataIC50: 1.91nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589881(US11559538, Example 133)
Affinity DataIC50: 628nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589881(US11559538, Example 133)
Affinity DataIC50: 1.37nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589881(US11559538, Example 133)
Affinity DataIC50: 1.92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent