BDBM589812 US11559538, Example 69::US11559538, Example 70::US11559538, Example 71

SMILES CCOc1cc(c(C)cc1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=IEKWSYWJZATVRM-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589812   

LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 4.39nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 373nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 6.51nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 3.84nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 3nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 890nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 4.31nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 2.85nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 11nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 1.91E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589812(US11559538, Example 69 | US11559538, Example 70 | ...)
Affinity DataIC50: 18.8nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent