BDBM589792 US11559538, Example 111::US11559538, Example 49

SMILES CCCOc1cc(c(F)cc1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=DUMIUWQTBXATJX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589792   

LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 0.970nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 496nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 3.01nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 2.95nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 1.59nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 166nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589792(US11559538, Example 49 | US11559538, Example 111)
Affinity DataIC50: 3.21nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent