BDBM589761 US11559538, Example 24::US11559538, Example 56

SMILES CCOc1cc(ccc1OC)-c1cncc(n1)C1COB(O)C1

InChI Key InChIKey=JAWXDLZOKMUZBA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589761   

LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 0.990nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 163nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 2.24nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 1.33nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 2.81nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 446nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 68nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589761(US11559538, Example 24 | US11559538, Example 56)
Affinity DataIC50: 3.62nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent