BDBM589758 US11559538, Example 189::US11559538, Example 21::US11559538, Example 53

SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C

InChI Key InChIKey=PBCDQTPZNZNWEJ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589758   

LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 2.61nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 1.46E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 7.72nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 1.46nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 0.640nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 159nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 0.840nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 1.35nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 1.41nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 4.87nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 21 | US11559538, Example 189 |...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent