BDBM589746 US11559538, Example 10::US11559538, Example 11::US11559538, Example 41

SMILES CCOc1c(OC)ccc(-c2cncc(c2)C2COB(O)C2)c1C(F)F

InChI Key InChIKey=KTZRSFMCORMVBW-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589746   

LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 6.92nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 438nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 2.39nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 1.62nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 33.5nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 141nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 68.3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 6.85nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 397nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589746(US11559538, Example 10 | US11559538, Example 11 | ...)
Affinity DataIC50: 1.87nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent