BDBM589744 US11559538, Example 228::US11559538, Example 8

SMILES COc1ccc(cc1OCCO)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=BZGMPSVOHOGYPP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589744   

LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 6.32nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 2.57E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 7.78nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 14.2nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 2.42nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 0.760nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589744(US11559538, Example 8 | US11559538, Example 228)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent