BDBM589740 US11559538, Example 4::US20240083921, Compound A

SMILES CCCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1

InChI Key InChIKey=KXVKOYCGACSUPP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 589740   

LigandPNGBDBM589740(US11559538, Example 4 | US20240083921, Compound A)
Affinity DataIC50: 0.5nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589740(US11559538, Example 4 | US20240083921, Compound A)
Affinity DataIC50: 135nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589740(US11559538, Example 4 | US20240083921, Compound A)
Affinity DataIC50: 4.11nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589740(US11559538, Example 4 | US20240083921, Compound A)
Affinity DataIC50: 1.06nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Reistone Biopharma Company

US Patent
LigandPNGBDBM589740(US11559538, Example 4 | US20240083921, Compound A)
Affinity DataIC50: 0.300nMAssay Description:1. Experimental MaterialsName Brand Cat No.PDE4B1 enzyme BPS 60041Trequinsin TOCRIS 2337/10IMAP FP IPP Explorer Kit Molecular Device R8124FAM-cAMP Mo...More data for this Ligand-Target Pair
In DepthDetails
US Patent