BDBM588122 US11542247, Compound 12
SMILES COc1cc(CO)c2CN(CCN(c3ccc4ncn(-c5cnn(C)c5)c(=O)c4c3)c2c1F)C(C)C
InChI Key InChIKey=WPNVOENRSMBFRM-UHFFFAOYSA-N
Data 5 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 588122
Affinity DataKd: 1.59E+3nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 1.86E+3nMAssay Description:FGFR2: In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 2.04E+3nMAssay Description:FGFR3: In a final reaction volume of 30 uL, FGFR3 (h) (40 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: >3.02E+3nMAssay Description:FGFR4: In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: >3.02E+3nMAssay Description:KDR (VEGFR2): In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4...More data for this Ligand-Target Pair
Ligand InfoSimilars