BDBM587706 2-(2-ethoxy-3-pyridyl)-6-(1-ethylpropyl)-8- methyl-imidazo[1,5-a]pyrimidine::US11535611, Example 75

SMILES CCOc1ncccc1-c1ccn2c(nc(C)c2n1)C(CC)CC

InChI Key InChIKey=MNWITQKMYDXVBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587706   

LigandPNGBDBM587706(2-(2-ethoxy-3-pyridyl)-6-(1-ethylpropyl)-8- methyl...)
Affinity DataIC50: 244nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

LigandPNGBDBM587706(2-(2-ethoxy-3-pyridyl)-6-(1-ethylpropyl)-8- methyl...)
Affinity DataIC50: 36nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

LigandPNGBDBM587706(2-(2-ethoxy-3-pyridyl)-6-(1-ethylpropyl)-8- methyl...)
Affinity DataIC50: 394nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent