BDBM586133 US11530244, Compound 051

SMILES C[C@@H](O)[C@H]1CC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@@]2(C)C(=O)N[C@@H](CSCc2cccc(CSCCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](Cc3c[nH]c4ccc(F)cc34)C(=O)N[C@@H](Cc3c[nH]c4ccc(F)cc34)C(=O)N3CCC[C@H]3C(=O)N1)c2)C(N)=O

InChI Key InChIKey=UYTBZWJKJSZDPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 586133   

LigandPNGBDBM586133(US11530244, Compound 051)
Affinity DataIC50: 50nMAssay Description:A set of cyclic polypeptides were identified to inhibit the interaction between human PCSK9 and human LDLR. Each polypeptide has an N-terminal amino ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM586133(US11530244, Compound 051)
Affinity DataIC50: 50nMAssay Description:The PCSK9 Alexa FRET Standard assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent A (KD=83 nM). A s...More data for this Ligand-Target Pair
In DepthDetails
US Patent