BDBM585939 US11530237, Compound 110::US11530237, Compound 128::US11542297, Compound 246

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cccc(F)c2n1

InChI Key InChIKey=UUSZMYJHIGRWKJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 585939   

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 10nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 30nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails
US Patent