BDBM585838 US11530229, Compound 53
SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(NC(=O)c2cc(CN3CCC4(CC4)C3)cc(n2)C2CC2)c1
InChI Key InChIKey=VXBDPUGJXWTSSH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 585838
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Nurix Therapeutics
US Patent
Nurix Therapeutics
US Patent
Affinity DataIC50: 1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair